One Broadway
14th Floor
Cambridge, MA 02142
United States
857 357 7000
https://www.nuvalent.com
版塊: Healthcare
行業: Biotechnology
全職員工: 92
名稱 | 頭銜 | 支付 | 行使價 | 出生年份 |
---|---|---|---|---|
Dr. James R. Porter Ph.D. | CEO, President & Director | 998.02k | 無 | 1976 |
Prof. Matthew D. Shair Ph.D. | Founder, Head of Scientific Advisory Board & Director | 235k | 無 | 1969 |
Dr. Christopher D. Turner M.D. | Chief Medical Officer | 714.26k | 無 | 1969 |
Dr. Benjamin Lane Ph.D. | Senior Vice President of Technical Operations | 無 | 無 | 無 |
Ms. Deborah Ann Miller J.D., Ph.D. | Chief Legal Officer & Secretary | 595.96k | 無 | 1976 |
Mr. Matthew Metivier | Senior Vice President of Human Resources | 無 | 無 | 無 |
Ms. Darlene Noci | Chief Development Officer | 無 | 無 | 1978 |
Mr. Henry Pelish Ph.D. | Senior Vice President of Drug Discovery | 無 | 無 | 無 |
Mr. John Soglia Ph.D. | Senior Vice President of Translational Development | 無 | 無 | 無 |
Ms. Perrin Wilson B.S., Ph.D. | Senior Vice President of Business Development & Strategy | 無 | 無 | 無 |
Nuvalent, Inc., a clinical stage biopharmaceutical company, engages in the development of therapies for patients with cancer. Its lead product candidates are NVL-520, a novel ROS1-selective inhibitor to address the clinical challenges of emergent treatment resistance, central nervous system (CNS)-related adverse events, and brain metastases that may limit the use of ROS1 tyrosine kinase inhibitors (TKIs) for patients with ROS proto-oncogene 1 (ROS1)-positive non-small cell lung cancer (NSCLC) which is under the phase 2 portion of the ARROS-1 Phase 1/2 clinical trial; NVL-655, a brain-penetrant ALK-selective inhibitor, to address the clinical challenges of emergent treatment resistance, CNS-related adverse events, and brain metastases that might limit the use of first-, second-, and third-generation ALK inhibitors that is under the phase 2 portion of the ALKOVE-1 Phase 1/2 clinical trial; and NVL-330, a brain-penetrant human epidermal growth factor receptor 2 (HER2)-selective inhibitor designed to treat tumors driven by HER2ex20, brain metastases, and avoiding treatment-limiting adverse events including due to off-target inhibition of wild-type EGFR, which is expected to initiate phase 1 trial. The company was incorporated in 2017 and is headquartered in Cambridge, Massachusetts.
截至 2024年4月29日 止,Nuvalent, Inc. 的 ISS 管治質素評分為 9。 Pillar 分數正在審核中:7;董事會:7;股東權利:10;現金賠償:9。